January 13, 2025Open Access

Danshen injection ameliorates unilateral ureteral obstruction-induced renal fibrosis by inhibiting ferroptosis via activating SIRT1/GPX4 pathway

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Abstract

Taken together, our results indicated that DSI could protect against ferroptosis to attenuate renal fibrosis by activating the SIRT1/GPX4 pathway. It is expected to be a potential agent to treat renal fibrosis.

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Cao et al. (Mon,) studied this question.

synapsesocial.com/papers/69d90176183921ebcaae45c8 https://doi.org/https://doi.org/10.3389/fphar.2024.1503628

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