April 21, 2020Open Access
View Full PaperThe A4 study: β‐amyloid and cognition in 4432 cognitively unimpaired adults
Key Points
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Abstract
Clinical trials for cognitively unimpaired β-amyloid-positive individuals will include a large number of individuals where mechanisms downstream from β-amyloid pathology are already activated. These findings have implications for primary and secondary prevention of Alzheimer's disease.