July 10, 2017Open Access

Inhibition of LIN28B impairs leukemia cell growth and metabolism in acute myeloid leukemia

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Abstract

In sum, these results uncover a novel mechanism of an important regulatory signaling, LIN28B/let-7/IGF2BP1, in leukemogenesis and provide a rationale to target this pathway as effective therapeutic strategy.

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Zhou et al. (Mon,) studied this question.

synapsesocial.com/papers/69da11050d540cafc58383cb https://doi.org/https://doi.org/10.1186/s13045-017-0507-y

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