What are the survival outcomes of combined multimodal treatment in patients with Ewing sarcoma of the head and neck?
Combined multimodal treatment including surgical resection and adjuvant chemoradiotherapy yields high 5-year overall and relapse-free survival in head and neck Ewing sarcoma.
Combined multimodal treatment resulted in a 5-year OS and RFS of 87% and 75%, respectively. Aggressive surgical resection with adjuvant chemoradiotherapy should be considered. Although negative margin surgery is the goal, subtotal resection may be acceptable in the setting of adjuvant treatment.
Olson et al. (Sun,) studied this question.