In a 71-year-old patient with an LVAD, incessant ventricular fibrillation was hemodynamically tolerated, suggesting routine ICD shock therapy may cause unnecessary trauma and should be reconsidered.
Case Report (n=1)
Routine use of ICD shock therapy in LVAD patients should be reconsidered, as they can remain hemodynamically stable during ventricular arrhythmias, making shocks unnecessarily painful.
Background and Clinical Significance: Patients with a left ventricular assist device (LVAD) are at risk of ventricular arrhythmias, which are generally hemodynamically tolerated if they occur. In such cases, patients may experience painful implantable cardioverter-defibrillator (ICD) shocks. Case Presentation: A 71-year-old patient with a history of dilated cardiomyopathy caused by a phospholamban (PLN) gain-of-function mutation, with a primary prevention ICD and an LVAD, presented with multiple ICD shocks which she experienced as painful and traumatic. She was found to have ongoing ventricular fibrillation with apparent hemodynamic stability. Conversion to sinus rhythm was achieved through intravenous administration of antiarrhythmic drugs followed by external defibrillation using stacked shocks. Due to the traumatic nature of the shocks, the shock function of the ICD was turned off. Nearly two months later, the patient presented for a second time and was again found to have ventricular fibrillation which had been present for at least six weeks. Conversion to sinus rhythm was unsuccessful and the patient was discharged to her home with an advanced care plan and her LVAD was deactivated. The patient died two months later. Conclusions: Patients with an LVAD can remain hemodynamically stable for prolonged periods of time during ventricular arrhythmias. ICD shocks are therefore mostly experienced as painful and even traumatic. Therefore, the routine use of ICD shock therapy in patients with an LVAD should be reconsidered. Adjustment of ICD programming to higher rates and longer detection may be warranted. Further investigation is warranted regarding a switch to devices with an alarm function rather than therapies for tachyarrhythmias.
Noordman et al. (Fri,) conducted a case report in Ventricular fibrillation in a patient with an LVAD and ICD (n=1). ICD shock therapy was evaluated. In a 71-year-old patient with an LVAD, incessant ventricular fibrillation was hemodynamically tolerated, suggesting routine ICD shock therapy may cause unnecessary trauma and should be reconsidered.