July 3, 1996

Larynx Preservation in Pyriform Sinus Cancer: Preliminary Results of a European Organization for Research and Treatment of Cancer Phase III Trial

Key Points

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Abstract

Larynx preservation without jeopardizing survival appears feasible in patients with cancer of the hypopharynx. On the basis of these observations, the EORTC has now accepted the use of induction chemotherapy followed by radiation as the new standard treatment in its future phase III larynx preservation trials.

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Cite This Study

Lefebvre et al. (Wed,) studied this question.

synapsesocial.com/papers/69dbddb7eb8801008ea3c07d https://doi.org/https://doi.org/10.1093/jnci/88.13.890

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Larynx Preservation Using Induction Chemotherapy plus Radiation Therapy as an Alternative to Laryngectomy in Advanced Head and Neck Cancer A Long-Term Follow-up Report1991 · 101 citations
2A Multiple Testing Procedure for Clinical Trials1979 · 3,351 citations
3Neoadjuvant Chemotherapy with Carboplatin/5-Fluorouracil in Head and Neck Cancer2009 · 45 citations
4Evaluation of survival data and two new rank order statistics arising in its consideration.1966 · 7,573 citations
5Intensive induction chemotherapy and radiation for organ preservation in patients with advanced resectable head and neck carcinoma.1994 · 65 citations

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