Prognostic Significance of Hypoalbuminemia in Maintenance Avelumab Therapy After First‐Line Chemotherapy for Metastatic Urothelial Carcinoma: A Multicenter Real‐World Study ( YUSHIMA Study)

Key Points

• The study aims to evaluate the prognostic significance of hypoalbuminemia in patients with metastatic urothelial carcinoma receiving maintenance avelumab therapy post-chemotherapy.
• Conducted a multicenter real-world study
• Analyzed the association between hypoalbuminemia and outcomes in patients
• Examined nutritional status management in relation to treatment efficacy.
• Hypoalbuminemia was identified as an independent prognostic factor
• Patients with preserved nutritional status showed improved efficacy of avelumab therapy
• Nutritional interventions may enhance treatment outcomes.