AbstractBackground: Periodontitis is a chronic inflammatory disease characterized by progressive destruction of the periodontal supporting tissues, often leading to the formation of deep infrabony defects. These defects pose significant functional and esthetic challenges and are commonly resistant to non-surgical periodontal therapy alone. While conventional surgical approaches such as open flap debridement improve access and pocket reduction, true periodontal regeneration remains limited. Hence, regenerative modalities using bone grafts and biologic agents like platelet rich fibrin have gained prominence to promote restoration of the lost periodontal apparatus.Aim: The aim of this study was to evaluate the role of a Freeze Dried bone graft substitute in the management of a circumferential infrabony defect in a mandibular left second molar in a patient diagnosed with localised periodontitis.Methodology: A circumferential defect of 6 mm around the mandibular molar was evident after debridement. The defect was filled up with a FDBA bone graft substitute and covered with a PRF membrane.Results: The site showed significant bony fill at the end of 9 months with reduction in probing depth to normal. The results were well maintained at the time of last follow- up at 12 months postoperatively.Conclusion: The use of freeze dried bone allograft in combination with platelet rich fibrin demonstrated predictable and stable periodontal regeneration in the management of a circumferential infrabony defect, with sustained clinical and radiographic improvements observed up to 12 months post-operatively.
Soumya Parmar (Sat,) studied this question.