September 13, 2022Open Access

The Single-Cell Immunogenomic Landscape of B and Plasma Cells in Early-Stage Lung Adenocarcinoma

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Abstract

While TIBs are highly enriched in LUADs, they are poorly characterized. This study provides a much-needed understanding of the transcriptional, clonotypic states and phenotypes of TIBs, unraveling their potential roles in the immunopathology of early-stage LUADs and constituting a road map for the development of TIB-targeted immunotherapies for the treatment of this morbid malignancy. This article is highlighted in the In This Issue feature, p. 2483.

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Hao et al. (Tue,) studied this question.

synapsesocial.com/papers/69deaabd40ea065679558f7c https://doi.org/https://doi.org/10.1158/2159-8290.cd-21-1658

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