Ezetimibe (discovery and medicinal chemistry)
This article provides a perspective on the medicinal chemistry and discovery process of the cholesterol absorption inhibitor ezetimibe.
ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTThe Discovery of Ezetimibe: A View from Outside the ReceptorJohn W. CladerView Author Information Cardiovascular and CNS Medicinal Chemistry Department, Schering-Plough Research Institute, 2015 Galloping Hill Road, Kenilworth, New Jersey 07033-0539 Cite this: J. Med. Chem. 2004, 47, 1, 1–9Publication Date (Web):December 9, 2003Publication History Received9 June 2003Published online9 December 2003Published inissue 1 January 2004https://pubs.acs.org/doi/10.1021/jm030283ghttps://doi.org/10.1021/jm030283greview-articleACS PublicationsCopyright © 2004 American Chemical SocietyRequest reuse permissionsArticle Views6059Altmetric-Citations284LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Absorption,Anatomy,Cholesterol,Inhibitors,Metabolism Get e-Alerts
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John W. Clader (Tue,) studied this question.
synapsesocial.com/papers/69dec24d741e97d2d4e941db — DOI: https://doi.org/10.1021/jm030283g
John W. Clader
Merck & Co., Inc., Rahway, NJ, USA (United States)
Journal of Medicinal Chemistry
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