January 1, 2013Open Access

Differential mortality rates in major and subthreshold depression: meta-analysis of studies that measured both

Structured PICO

Is there a difference in mortality rates between major and subthreshold depression?

Population

Patients in studies that measured both major and subthreshold depression

Intervention

Major depression

Comparator

Subthreshold depression

Outcome

Mortality rateshard clinical

Major and subthreshold depression have a comparable overall impact on excess mortality, despite a small difference in rates.

Abstract

Although excess mortality may be somewhat higher in major than in subthreshold depression, the difference is small and the overall impact on excess mortality is comparable.

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