What question did this study set out to answer?

The study aims to assess pulmonary function deficits in childhood acute lymphoblastic leukaemia (ALL) survivors and their clinical associations.

April 15, 2026Open Access

Pulmonary Function Deficit and Clinical Associations in Childhood Acute Lymphoblastic Leukaemia Survivors: A National Retrospective ALL‐STAR Lungs Cohort Study

Key Points

The study aims to assess pulmonary function deficits in childhood acute lymphoblastic leukaemia (ALL) survivors and their clinical associations.
Conducted a national retrospective cohort analysis of childhood ALL survivors.
Examined pulmonary function specifically after stem cell transplantation and pulmonary disease.
Analyzed small airway function and diffusing capacity for better monitoring.
Pulmonary function deficits were frequently observed in childhood ALL survivors.
Deficits were particularly notable in those who underwent stem cell transplantation.
Tailored monitoring strategies are recommended for early detection and intervention.

Abstract

Pulmonary function deficit was frequent in childhood ALL survivors, especially after stem cell transplantation or pulmonary disease. Tailored long-term pulmonary monitoring, including small airway function and diffusing capacity, may aid in timely detection and intervention.

Pulmonary Function Deficit and Clinical Associations in Childhood Acute Lymphoblastic Leukaemia Survivors: A National Retrospective ALL‐STAR Lungs Cohort Study

Key Points

Abstract

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