Following the Formation of Single-Chain Nanoparticles Generated by Interblock Crosslinking within Diblock Copolymers: A Monte Carlo Simulation Study with Adjustable Interaction Strength between the Blocks

Key Points

• The research aims to investigate the folding and crosslinking behavior of diblock copolymers in solution.
• Utilized a bead-spring model for polymer simulations
• Conducted Monte Carlo simulations to analyze crosslinking
• Investigated the effects of interaction strength between blocks
• Demonstrated formation of single-chain nanoparticles from diblock copolymers
• Found that adjustable interaction strength significantly affects nanoparticle properties
• Showed successful folding of copolymers under simulation conditions