Rapid Drug Desensitization to Platinum-based Chemotherapy Agents: A Single-center Experience

Key Points

• The aim is to evaluate the effectiveness of rapid drug desensitization to platinum-based chemotherapy agents.
• Single-center experience reviewed cases of rapid desensitization procedures.
• Comparison of hypersensitivity reactions (HSRs) across different platinum agents.
• Analysis of outcomes based on gender and type of platinum agent.
• High success rates in desensitization were achieved across platinum agents.
• HSRs to oxaliplatin were significantly more frequent among male patients.
• Clinical outcomes after desensitization were comparable across agents.