Heparin-functionalized chitosan-poly(ε-caprolactone) nanoparticles loaded with quinine for selective targeting of infected erythrocytes and enhanced antiplasmodial efficacy | Synapse
April 16, 2026
Heparin-functionalized chitosan-poly(ε-caprolactone) nanoparticles loaded with quinine for selective targeting of infected erythrocytes and enhanced antiplasmodial efficacy
Key Points
The research aims to develop a targeted nanomedicine that enhances the treatment efficacy for malaria.
Developed heparin-functionalized chitosan-poly(ε-caprolactone) nanoparticles.
Loaded nanoparticles with quinine for targeted delivery.
Evaluated efficacy and safety for malaria therapy.
Demonstrated improved targeting of infected erythrocytes.
Enhanced antiplasmodial efficacy noted in laboratory tests.
Abstract
These findings demonstrate a targeted nanomedicine platform with improved efficacy and safety for malaria therapy, suitable for further preclinical studies.