Association of uric acid-to-HDL cholesterol ratio and coronary atherosclerotic heart disease in patients with and without CKD | Synapse
April 17, 2026Open Access
Association of uric acid-to-HDL cholesterol ratio and coronary atherosclerotic heart disease in patients with and without CKD
Key Points
To examine the relationship between the uric acid-to-HDL cholesterol ratio and the risk of coronary atherosclerotic heart disease, particularly in patients with and without chronic kidney disease (CKD).
Observed uric acid-to-HDL cholesterol ratios in participants
Evaluated coronary heart disease prevalence
Compared findings across CKD and non-CKD populations
Identified uric acid-to-HDL cholesterol ratio as an independent risk factor for coronary heart disease
Found increased odds ratios for heart disease risk in populations without CKD
Highlighted significance of the ratio for risk assessment in cardiovascular health
Abstract
UHR is an independent risk factor for coronary heart disease, with higher adjusted OR values and more significant independent risk effects in non-CKD populations.