What question did this study set out to answer?

To explore the occurrence of licorice-induced pseudoaldosteronism in an infant treated with rikkunshito.

April 17, 2026Open Access

Licorice‐Induced Pseudoaldosteronism Caused by Rikkunshito in an Extremely Low Birth Weight Infant

Key Points

To explore the occurrence of licorice-induced pseudoaldosteronism in an infant treated with rikkunshito.
Case report of an extremely low birth weight infant
Monitored symptoms like hypokalemia and metabolic alkalosis
Treatment involved rikkunshito and potassium supplementation
Infant experienced persistent hypokalemia and metabolic alkalosis after rikkunshito treatment
Symptoms resolved after discontinuing rikkunshito and providing potassium supplementation

Abstract

We report an extremely low birth weight infant with gastroesophageal reflux disease who developed persistent hypokalemia and metabolic alkalosis after treatment with rikkunshito. These findings gradually resolved after discontinuation of rikkunshito and potassium supplementation, suggesting licorice-induced pseudoaldosteronism.

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Cite This Study

Nakayama et al. (Thu,) studied this question.

synapsesocial.com/papers/69e1cfe05cdc762e9d858dba https://doi.org/https://doi.org/10.1111/ped.70407

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