Tuning the hydrophobicity of glycine ester through N -acylation and introducing quaternary pyridinium groups enable the selectivity against Gram-positive bacteria | Synapse
April 19, 2026Open Access
Tuning the hydrophobicity of glycine ester through N -acylation and introducing quaternary pyridinium groups enable the selectivity against Gram-positive bacteria
Key Points
To explore how tuning glycine ester affects its hydrophobicity and selectivity towards Gram-positive bacteria.
Utilized N-acylation to modify glycine ester structure
Introduced quaternary pyridinium groups
Assessed effects on bacterial membrane integrity
QPyNAGe showed enhanced selectivity against Gram-positive bacteria
Demonstrated impact on bacterial membrane integrity