What question did this study set out to answer?

This research aimed to evaluate the feasibility and impact of digital lifestyle interventions on fatigue in myasthenia gravis patients.

April 20, 2026Muscle & Nerve2 citationsOpen Access

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Digital Phenotyping and Lifestyle Intervention in Patients With Myasthenia Gravis ( DIG ‐ MG ): A Randomized Controlled Trial of Feasibility, Adherence, and Effects on Fatigue

MNMaja NorlingUppsala University NEN ErikssonUppsala University EWElisabet WesterbergUppsala University Hospital

Key Points

This research aimed to evaluate the feasibility and impact of digital lifestyle interventions on fatigue in myasthenia gravis patients.
Conducted a randomized controlled trial
Assessed feasibility and adherence to digital lifestyle interventions
Monitored fatigue-related factors using DHT technology
Digital lifestyle interventions were feasible and well-accepted among participants.
No significant improvement was observed in MG-ADL or FSS scores.
Reduced REM sleep was identified as a fatigue-related factor requiring further study.

Abstract

Digital lifestyle interventions were feasible and well-accepted but did not improve MG-ADL or FSS in this unusually active population. However, DHT-based monitoring may support individualized follow-up, and reduced REM sleep warrants further investigation as a fatigue-related factor.

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Digital Phenotyping and Lifestyle Intervention in Patients With Myasthenia Gravis ( DIG ‐ MG ): A Randomized Controlled Trial of Feasibility, Adherence, and Effects on Fatigue

Key Points

Abstract

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