Background The cardiometabolic index (CMI) is composed of obesity and lipid indices, including the waist‐to‐height ratio (WHtR) and the triglyceride‐to‐HDL‐C (TG/HDL‐C) ratio. Previous studies have examined the clinical utility of CMI in diagnosing diabetes, cardiovascular disease (CVD), and metabolic syndrome, all of which are common comorbidities in patients with psoriasis. Objective This study aims to investigate the potential association between CMI and psoriasis. Methods We performed a cross‐sectional analysis utilizing data from five cycles (2003–2006 and 2009–2016) of the National Health and Nutrition Examination Survey (NHANES), representative of the U.S. population. To investigate the association between CMI and psoriasis, we applied binary logistic regression, restricted cubic spline (RCS) modeling, and subgroup analyses. Results A total of 8342 participants were included, of whom 235 (3.12%) reported having psoriasis. After adjusting for covariates, higher CMI levels were associated with an increased likelihood of psoriasis. Psoriasis prevalence demonstrated a significant upward trend across CMI quartiles ( p for trend: Model 1, 0.005; Model 2, 0.0042; and Model 3, 0.0015). RCS analysis indicated a nonlinear relationship between CMI and psoriasis ( p overall = 0.0017, p nonlinear = 0.0033), showing an overall upward trend. Subgroup analysis showed no significant interactions across covariates ( p > 0.05). Conclusion CMI levels are significantly positively correlated with psoriasis prevalence, suggesting that CMI could serve as a convenient and accessible marker for identifying psoriasis.
Ren et al. (Thu,) studied this question.