Purpose: The purpose of this study was to investigate the association between axial length and PERG response among myopic patients. Materials and Methods: A cross-sectional study was conducted among 37 myopic subjects. All patients had a full ophthalmic examination including the measurement of visual acuity, intraocular pressure, degree of refractive error, axial length, biomicroscopic evaluation of the anterior segment, fundoscopy, and PERG. Association between PERG responses (P50 and N95 amplitude time and P50 and N95 implicit time) and axial length was established. Statistical Significance was considered if P < 0.05. Results: There was significant negative correlation between P50 amplitude and increased in axial length ( r = −0.274, P < 0.05). However, there was insignificant correlation between N95 amplitude and increase in axial length ( r = 0.056, P = 0.63). Similarly, a significant positive correlation was found between P50 implicit time and N95 implicit time and increased axial length ( r = 0.271, P < 0.05 and r = 0.403, P < 0.01). Similarly, a nonsignificant relationship was found between P50 amplitudes and N95 amplitudes and spherical equivalent refraction (SER) ( r = 0.227, P = 0.05 and r = 0.039, P = 0.74, respectively). However, there was significant negative correlation between P50 implicit time and N95 implicit time and SER ( r = −0.299, P = 0.01 and r = −0.408, P < 0.01). Conclusion: Reduced amplitudes and delayed PERG responses are significantly correlated with increased axial length and SER in myopes.
Chaurasiya et al. (Wed,) studied this question.