Development of a diagnostic scale for chronic heart failure with yang deficiency and blood stasis syndrome based on the literature review，Delphi method，and clinical investigation

Key Result

A novel 15-item diagnostic scale for chronic heart failure with yang deficiency and blood stasis syndrome achieved high diagnostic accuracy with 90.67% sensitivity and 92.21% specificity.

Key Points

• This research aims to create a diagnostic scale for chronic heart failure characterized by yang deficiency and blood stasis using multifaceted evidence.
• Conducted literature analysis and expert brainstorming to establish an initial item pool.
• Utilized the Delphi method and multi-center clinical data to refine items with factor and analytical methods.
• Employed ROC curve analysis to determine the optimal diagnostic model and threshold.
• Developed a scale with 15 core items across four dimensions related to symptoms and signs.
• Achieved a diagnostic threshold of 169.5, with sensitivity at 90.67% and specificity at 92.21%.