What question did this study set out to answer?

To assess adherence to EAU-AUA guidelines in managing upper tract urothelial carcinoma across multiple centers.

April 25, 2026Minerva Urology and Nephrology0 citations

Real-world multicenter adherence to international guidelines in the management of upper tract urothelial carcinoma: insights from the ROBUUST 2.0 Registry

MFMariaconsiglia FerrieroNational Cancer Institute GTGabriele TUDERTIIstituti di Ricovero e Cura a Carattere Scientifico FPFlavia ProiettiPoliclinico Umberto I

Key Points

To assess adherence to EAU-AUA guidelines in managing upper tract urothelial carcinoma across multiple centers.
Analysis of real-world data from the ROBUUST 2.0 Registry
Focus on key indicators such as perioperative bladder instillation, lymph node dissection, and adjuvant chemotherapy
Poor adherence to guidelines for perioperative bladder instillation of chemotherapy noted
Inadequate performance of lymph node dissection identified
Suboptimal administration of adjuvant chemotherapy for advanced cases observed

Abstract

The present contemporary "real world" data suggests poor adherence to current EAU-AUA guidelines for key indicators of quality care such as perioperative bladder instillation of chemotherapy, performance of LND and administration of adjuvant chemotherapy for advanced disease. These findings highlight the need of improving the implementation of these guideline driven treatment strategies.

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