Comment on ‘Collagen I–DDR1 Signaling as a Driver of Keloid Inflammation: Mechanistic Expansion of 1 the ARF6–DDR1 Axis’: reply from authors

Key Points

• This response aims to clarify and expand upon the mechanisms discussed in relation to collagen I–DDR1 signaling in keloid inflammation.
• Address previous comments on the collagen I–DDR1 signaling pathway
• Discuss the role of ARF6 in this signaling process
• Clarify points of misunderstanding regarding the mechanistic implications
• Reinforces the significance of collagen I–DDR1 signaling in keloid pathology
• Highlights new insights into the ARF6–DDR1 axis
• Confirms the importance of understanding these pathways for future therapeutic approaches