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This review examines the prevalence of HSV-2 IgG and its implications for pregnant individuals.

April 27, 2026Journal of Pregnancy0 citationsOpen Access

Global Seroprevalence (HSV‐2 IgG), Risk Factors, and Outcomes of Genital Herpes Infection During Pregnancy: A Systematic Review and Meta‐Analysis

NSNader SalariKermanshah University of Medical Sciences AGAshkan Fatemi GoharKermanshah University of Medical Sciences FLFateme LotfiKermanshah University of Medical Sciences

Key Points

This review examines the prevalence of HSV-2 IgG and its implications for pregnant individuals.
Conducted a systematic review and meta-analysis of existing literature on HSV-2 during pregnancy.
Identified risk factors associated with genital herpes infection and its complications.
Analyzed data to provide comprehensive insights into public health recommendations.
Identified significant complications of HSV-2 during pregnancy, requiring increased awareness.
Highlighted the necessity of public health interventions to reduce infection rates.
Emphasized the importance of prevention and follow-up measures for pregnant individuals.

Abstract

Given the seroprevalence (HSV-2 IgG), associated factors, and significant complications of contracting this infection during pregnancy, it is recommended that relevant authorities provide the necessary resources to increase awareness among the public and apply appropriate prevention and follow-up measures to minimize the risk of infection.

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