What question did this study set out to answer?

The study aimed to explore how sleep duration and diet quality affect IgG levels and biochemical markers in vaccinated individuals.

May 3, 2026Open Access

İki Doz COVID-19 Aşısı Yapılan Gönüllülerde Diyet Kalitesi ve Uyku Süresinin IgG Düzeyleri ve Serum Lipidleri ile İlişkisi

Key Points

The study aimed to explore how sleep duration and diet quality affect IgG levels and biochemical markers in vaccinated individuals.
61 volunteers who received two doses of the COVID-19 vaccine were assessed.
Diet quality and nutrient intake were evaluated using the Dietary Quality Index-2015 and CeviCal program.
Biomarkers, anthropometric measurements, and serum IgG levels were measured alongside physical activity and sleep duration.
Short sleep duration correlated with higher fasting blood sugar levels (p<0.05).
Long sleep duration was associated with higher IgG levels compared to normal sleep duration (p=0.029).
Poor diet quality resulted in higher total cholesterol and waist circumference (p<0.05).

Abstract

Aim: This study aimed to investigate the associations of sleep duration, diet quality, and body fat classification with IgG levels, biochemical parameters, and anthropometric measurements in volunteers who received two doses of the COVID-19 vaccine.Method: A total of 61 volunteers participated in the study. Biomarkers, anthropometric measurements, physical activity, sleep duration, and serum IgG levels were assessed. Dietary Quality Index-2015 (DQI-2015) and nutrient intake were calculated using the CeviCal program based on food frequency data. Results: Individuals with short sleep duration had significantly higher fasting blood sugar levels compared to those with normal sleep duration (p0.05). Individuals with long sleep duration had higher serum IgG levels compared to those with normal sleep duration (p=0.029). LDL cholesterol levels were lower in individuals who consumed alcohol, while T3 levels were lower in smokers (p0.05). Total cholesterol, non-HDL cholesterol, and waist circumference values were higher in individuals with poor diet quality (p0.05). Total cholesterol and triglyceride levels were found to be higher in obese individuals (p0.05). The increase in IgG levels was found to be associated with an increase in fasting serum glucose levels, and a moderate positive correlation was found between these parameters (p0.001, r=0.445). IgG levels were significantly lower in individuals with high daily vitamin C intake (p=0.037). 25(OH)D levels were lower in individuals with active physical activity levels compared to inactive individuals (p0.05).Conclusion: Short sleep duration, poor diet quality, and obesity have been associated with adverse changes in glucose, lipid profile, and anthropometric measurements. Long sleep duration has been associated with higher IgG levels, while high vitamin C intake has been associated with lower IgG levels. Additionally, increased IgG levels have been associated with higher glucose levels. Larger sample studies are needed to confirm these findings.

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Cite This Study

Fatih Cesur (Sat,) studied this question.

synapsesocial.com/papers/69f6e5308071d4f1bdfc5f4e https://doi.org/https://doi.org/10.38079/igusabder.1627062

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