Alkyne migratory functionalization via C(sp3)–C(sp3) bond transposition | Synapse
May 8, 2026Open Access
Alkyne migratory functionalization via C(sp3)–C(sp3) bond transposition
Key Points
This research aims to develop a method for the stereoconvergence of regioisomers via alkyne migratory functionalization.
Utilized a transposition process for C(sp3)–C(sp3) bond conversion.
Focused on competitive in situ hydrofunctionalization mechanisms.
Successfully achieved consistent migration products from previously undesired regioisomers.
Indicated improved efficiency in the alkyne functionalization process.
Abstract
) bond transposition process, which enables the stereoconvergence of undesired regioisomers from competitive in situ hydrofunctionalization into consistent migration products.