Objectives/Goals: Translational research teams span varied roles, disciplines, and institutions. They rely on information to collaborate, communicate, and coordinate. Information should flow seamlessly for collaborative success, yet we know little about the collective information needs and challenges of such teams, representing a translational science problem. Methods/Study Population: We report on the Information Management Prototype for Clinical and Translational Research (IMPACT-CTR) study which explored how clinical and translational research teams (CTRTs) manage their information while conducting collaborative research. Participants across 11 US-based CTRTs (n=52) participated in brief surveys and interviews about their collaborative processes. We are following the Translational Team Science Hierarchy of Needs (Kelly et al., 2023) framework in our thematic analyses, where we are sequentially examining: (1) the foundation of information infrastructure (tools and resources), (2) teams’ information management practices, and (3) how these practices affect psychological safety of team members, which then impact “translational nirvana” or the research synergy of CTRTs. Results/Anticipated Results: Preliminary analysis revealed that information was crucial to CTRTs’ functionality but often overlooked. Team members moved through the research lifecycle by juggling numerous types of information spread across multiple tools, while balancing their personal information styles with those of the collective. Subsequent analyses will investigate the challenges, workarounds, and lessons CTRT members have learned while managing their information and relying on each other as information resources, and the extent to which these factors impact their scientific and operational work, as well as their team culture. We will thus develop and present a conceptual framework of how CTRTs’ information behaviors can facilitate or impede high-impact collaborative research. Discussion/Significance of Impact: We will present reproducible team science practices that can enhance the process of scientific research through evidence-based information management practices that are both effective and feasible for CTRTs. In doing so, we will identify information-related barriers that hinder the efficiency of the translational research continuum.
Venkatesh et al. (Wed,) studied this question.