Acid-Catalyzed Skeletal Reorganization of Phenyloxirane Derivatives

Key Points

• This research investigates the skeletal rearrangement of -alkynylphenyl oxiranes under acid conditions.
• Performed reactions using Brønsted and Lewis acid catalysts.
• Analyzed a range of -alkynylphenyl oxirane derivatives to assess substrate tolerance.
• Conducted reactions under mild conditions.
• Skeletal rearrangements yielded indenylfuran and indanylbenzofuran frameworks.
• Transformations showed broad substrate tolerance and were generally insensitive to electronic effects.