Oleacein prevents metabolic dysfunction–associated hepatic steatosis and dyslipidaemia in ApoE-KO mice

Key Points

• This research aims to determine if oleacein can prevent metabolic dysfunction-related fatty liver disease and dyslipidaemia in mice lacking the ApoE gene.
• Utilized ApoE-KO mice to investigate oleacein's effects on metabolic factors.
• Evaluated cardiometabolic risk factors related to hepatic steatosis and dyslipidaemia.
• Oleacein significantly reduced markers of hepatic steatosis in treatment group versus control peer group.
• Dyslipidaemia was effectively lowered with oleacein, suggesting improved lipid profiles.