06 MCT Clonal Evolution Framework Integrated With genomic Parsener Pipeline

Key Points

• This research aims to create a framework for mapping genetic data to phenotypic biology via a genomic parser.
• Integrated MCT Clonal Evolution Framework with genomic parser for gene mapping.
• Utilized data from literature, including graphs and digital programs for analysis.
• Developed scripts and tumor math scripts for enhanced data comprehension.
• Identified gene-to-node mappings for BRCA1, TP53, and POLE illustrating their biological roles.
• Demonstrated that integrated methods highlight phenotypic biology relevant to genetic mutations.
• Contributed to an open-source project aimed at improving genomic data analysis frameworks.