Do echocardiographic markers of left atrial fibrosis (PA-TDI and LA reservoir strain) correlate with atrial fibrillation burden?
Echocardiographic markers of left atrial fibrosis (PA-TDI and LA reservoir strain) correlate with the progression and burden of atrial fibrillation.
= 0.43, p <0.001); controlling for age, hypertension, coronary artery disease, body mass index, severity of mitral regurgitation, left ventricular global longitudinal strain, and LA volume. In conclusion, PA-TDI and LA reservoir strain are negatively correlated in all subjects, irrespective of the presence or burden of AF. Patients with persistent AF have longer PA-TDI and impaired LA reservoir strain compared with paroxysmal AF and controls, suggesting increasing burden of fibrosis and LA structural remodeling in the progression of AF.
Leung et al. (Mon,) studied this question.