The aim is to explore the potential of VHH antibodies targeting FAPα in cancer treatment.
Development of structurally validated anti-FAPα VHH-Fc candidates.
Optimization of functional properties for enhanced immunotherapy efficacy.
Validated several anti-FAPα VHH-Fc candidates.
Demonstrated functional optimization for targeting stromal cells in solid tumors.
Abstract
stromal cells. Collectively, this work establishes a structurally validated and functionally optimized anti-FAPα VHH-Fc candidates for stromal-targeted immunotherapy in solid tumors.
Demander à l'IA
Like
Bookmark
Share
View Full Paper
Demander à l'IA
Like
Bookmark
Share
View Full Paper
Studies on single domain antibodies VHH against FAPα as potential cancer therapeutics | Synapse