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Dual-mode imaging combining photoacoustic and ultrasound modalities holds great promise for comprehensive tissue characterization. In traditional dual-mode imaging systems, however, the opaque ultrasound transducers are integrated in complex optical and ultrasound paths, leading to compromises in imaging efficiency and sensitivity. To address these challenges, we design and produce highly transparent Pb(Mg,Nb)O 3 -PbTiO 3 ceramics with exceptional transparency of 68%, alongside a remarkable ultrahigh piezoelectric d 33 of 1500 pC/N. Leveraging this material, we fabricate a high-sensitivity transparent piezoelectric ultrasound transducer (TPUT) with a center frequency of 16 MHz and a bandwidth of 30%, which seamlessly integrating ultrasound and photoacoustic capabilities into one system to achieve simultaneous photoacoustic/ultrasound dual-mode imaging, showcasing a remarkable sensitivity for deep-tissue detection ( e.g. , 7.5 mm thick chicken breast meat). Additionally, in vivo photoacoustic imaging of subcutaneous microvasculature in a mouse ear was successfully achieved via 28 MHz TPUT. Our innovation not only advances imaging performance but also offers a cost-effective solution, paving the way for transformative biomedical imaging applications. • Eu-PMN-PT ceramics with high transparency of 68% and d 33 of 1500 pC/N were produced • The origin of high transparency and d 33 in the ceramic was discussed in detail • High-sensitivity transparent piezoelectric ultrasound transducer was fabricated • Photoacoustic and ultrasound dual-mode imaging of phantom was successfully achieved • A remarkable sensitivity for deep-tissue detection (7.5 mm chicken meat) was found • In vivo photoacoustic imaging of microvasculature in mouse ear was validated
Guo et al. (Fri,) studied this question.