AS-IV’s protective potential against inflammatory injury via miR-320b/PTEN axis in acute ischemic stroke

Key Points

• This research aims to evaluate AS-IV's protective potential against inflammatory injury during acute ischemic stroke.
• Cells were subjected to OGD/R conditions to simulate ischemic conditions.
• The effects of AS-IV on cell viability, inflammation, and apoptosis were assessed via the miR-320b/PTEN axis.
• AS-IV significantly improved cell viability under OGD/R conditions.
• Inflammation and apoptosis were inhibited by AS-IV through modulation of the miR-320b/PTEN signaling pathway.