What is the clinical evidence from this study?

Study design: Cohort. Population: Cardiometabolic risk (n=258). Intervention: Physical activity and sedentary time. Primary outcome: Cardiometabolic risk score (CRS) (β = 0.159, p=0.049).

October 2, 2018Open Access

Longitudinal associations of physical activity and sedentary time with cardiometabolic risk factors in children

Key Result

Increased vigorous and moderate-to-vigorous physical activity and decreased sedentary time were associated with reduced overall cardiometabolic risk in children (β = 0.159, P = 0.049).

Study Design

Type

Cohort (n=258)

Structured PICO

Does increased physical activity and decreased sedentary time improve cardiometabolic risk factors in children?

Population

258 children aged 6-8 years from a population sample

Intervention

Physical activity (PA) including vigorous (VPA), moderate-to-vigorous (MVPA), and light (LPA), and sedentary time (ST) assessed by a combined heart rate and movement sensor

Outcome

Cardiometabolic risk score (CRS) constructed from continuous age- and sex-adjusted z-scores for waist circumference, blood pressure, fasting insulin, glucose, triglycerides, and HDL cholesterolsurrogate

Increasing moderate-to-vigorous physical activity and decreasing sedentary time are associated with reduced cardiometabolic risk in children over a 2-year period.

Main Result

Effect estimate: β = 0.159

p-value: p=0.049

Abstract

BACKGROUND: ) in children. We therefore investigated these relationships among children. METHODS: The participants were a population sample of 258 children aged 6-8 years followed for 2 years. We assessed PA and ST by a combined heart rate and movement sensor; computed continuous age- and sex-adjusted z-scores for waist circumference, blood pressure, and fasting insulin, glucose, triglycerides, and high-density lipoprotein (HDL) cholesterol; and constructed a cardiometabolic risk score (CRS) of these risk factors. Data were analyzed using linear regression models adjusted for age, sex, the explanatory and outcome variables at baseline, and puberty. RESULTS: (β = 0.159, P = 0.049). CONCLUSIONS: Increased VPA and MVPA and decreased ST were associated with reduced overall cardiometabolic risk and major individual risk factors. Change in LPA had weaker associations with changes in these cardiometabolic risk factors. Our findings suggest that increasing at least moderate-intensity PA and decreasing ST decrease cardiometabolic risk in children.

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