in the International Journal of Women's Health, which investigated the clinical features, diagnosis, treatment, and prognosis of post-surgical abdominal wall endometriosis (AWE) in 187 patients.The authors proposed a depth-based classification system dividing AWE into three types: type I (skin and subcutaneous fat layer), type II (fascia or muscle layer), and type III (peritoneal layer), and demonstrated that type III AWE is associated with larger lesion size, longer operative time, and higher rates of mesh and drainage placement.The study provides valuable clinical data from a relatively large single-center cohort with a median follow-up of 43 months.While we commend the authors for their contribution to this underexplored field, we would like to raise several points that may further enhance the interpretation and clinical applicability of their findings.First, regarding the depth-based classification system, we wish to draw attention to a prior study by Wu et al 2 published in Archives of Gynecology and Obstetrics in 2023, which employed a virtually identical three-tier classification (type I: skin and subcutaneous tissue; type II: fascia and rectus abdominis; type III: peritoneum) in a larger cohort of 367 patients at Peking Union Medical College Hospital.Wu et al 2 similarly found that deeper invasion was associated with more severe clinical manifestations and higher surgical complexity, with a 5-year cumulative recurrence rate of 3.3%.However, this important antecedent study was not cited or discussed by Zhao et al 1 It is noteworthy that both independent studies arrived at remarkably consistent conclusions, which strengthens the validity of this classification approach.Furthermore, Piriyev et al 3 proposed an alternative classification using the fascia as a threshold to distinguish the degree of invasion in a multicenter study of 80 patients.A comparative discussion of these classification systems would have been valuable for the field.Second, the reported 3-year cumulative recurrence rate of 6.2% and the absence of identifiable risk factors warrant careful interpretation.Kim et al 4 reported strikingly different results in their single-institution study, with cumulative recurrence rates of 23.8% at 24 months and 39.1% at 60 months.This discrepancy may be attributable to differences in follow-up duration, recurrence definitions, surgical techniques, or patient populations.Notably, positive surgical margins have been consistently identified as the strongest predictor of AWE recurrence across multiple studies. 4,5While Zhao et al 1 described a resection margin of 0.5-1.0cm, the pathological margin status (R0/R1) was not reported.Given that only 10 recurrence events were observed among 187 patients, the statistical power for identifying risk factors through Cox regression analysis was inherently limited.The inclusion of margin status as a variable in the recurrence analysis could have provided more clinically actionable insights.Third, the discussion of emerging minimally invasive treatments, while acknowledged, could have been more comprehensively addressed.A recent systematic review by Razakamanantsoa et al 6 encompassing 2674 patients
Li et al. (Fri,) studied this question.