Positive End-Expiratory Pressure Is Associated With Apparent Increases in Single-Beat Left Ventricular End-Systolic Elastance: Implications of Stroke Volume Sensitivity | Synapse
May 17, 2026
Positive End-Expiratory Pressure Is Associated With Apparent Increases in Single-Beat Left Ventricular End-Systolic Elastance: Implications of Stroke Volume Sensitivity
Key Points
This research aims to investigate how positive end-expiratory pressure influences left ventricular end-systolic elastance and its relationship with stroke volume sensitivity.
Conducted a randomized trial
Analyzed the relationship between positive end-expiratory pressure and left ventricular elastance
Measured stroke volume sensitivity using cardiac metrics
Observed an increase in left ventricular end-systolic elastance with higher positive end-expiratory pressure
Increase in elastance correlated with improved stroke volume sensitivity