Protein binding regulates complex configuration: comparative analysis of three dynamically racemic europium( iii ) complexes

Key Points

• This research investigates how protein binding affects the structural configuration of europium(III) complexes, focusing on their enantiomeric forms.
• Comparative analysis of europium(III) complexes with human serum albumin and bovine serum albumin.
• Measurement of chiroptical properties to determine binding characteristics and enantiomer predominance.
• Eu(III) complex predominantly binds as the Λ enantiomer to human serum albumin.
• Binding to bovine serum albumin favors the Δ isomer, illustrating different binding preferences.