Hospital survivors of acute myocardial infarction aged ≤60 years demonstrated high overall survival rates of 96% at 1 year and 95% at 2 years, driven by a 58% prevalence of one-vessel disease.
Cohort (n=229)
What is the coronary anatomy and long-term prognosis of hospital survivors of acute myocardial infarction aged 60 years or younger?
Younger patients surviving an acute MI generally have a favorable prognosis driven by a high prevalence of single-vessel disease, suggesting prophylactic therapy should be targeted to identifiable high-risk subgroups.
Two hundred twenty-nine hospital survivors of acute myocardial infarction (MI) age 60 years or younger underwent coronary arteriography a median of 2 weeks after infarction and were followed a median of 24 months (range 6-62 months). For 62%, MI was the first presentation of coronary disease and 75% were in clinical Killip class I. Overall outcome was good: 96% survival at 1 year and 95% survival at 2 years. This was due to the high prevalence of patients with one-vessel disease (58%), with a survival of 99% at 1 year and 96% at 2 years. Only 9% of patients had three-vessel disease and they had an 85% survival at 1 year. Eleven patients died and 23 had coronary bypass surgery. In this cohort of younger patients (mean age 51 years), prophylactic therapy may not be justified because of the low mortality and should be reserved for identifiable high-risk groups.
Roubin et al. (Fri,) conducted a cohort in Acute myocardial infarction (n=229). Observational was evaluated on Overall survival at 1 year. Hospital survivors of acute myocardial infarction aged ≤60 years demonstrated high overall survival rates of 96% at 1 year and 95% at 2 years, driven by a 58% prevalence of one-vessel disease.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: