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Synchronous cultures of Escherichia coli B were produced under various environmental conditions. Analysis of the cell number data permitted the characterization of the generation time distribution for these organisms and the estimation of the mother-daughter generation time correlation coefficients. For all growth conditions, the distribution of generation times was found to be symmetrical with a coefficienoefficient was significantly negative at doubling times between 40 and 64 min. However, the results for a culture growing in succinate medium at 37 degrees C, which had a significantly greater generation time, yielded a correlation coefficient close to zero. Within the range of temperatures studied (26 to 37 degrees C), no significant effect on the correlation coefficient was observed.
Plank et al. (Thu,) studied this question.
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