Female sex is associated with a higher incidence of stroke and more negative clinical outcomes compared to men, highlighting the need to understand differential physiology and epidemiology.
This review highlights the significant sex differences in stroke epidemiology, physiology, and clinical presentation, emphasizing the higher burden and worse outcomes in women.
Stroke is a leading cause of death among women in the United States, and women are more affected by stroke than men. With women living longer than men, women experience not only a higher incidence of stroke but also more negative outcomes. Despite its lethal impact and high morbidity rate, the road from innovative bench research to improved clinical outcomes has been slow. This review explores the differential physiology, epidemiology, and clinical presentation of stroke between men and women, as well as the current status of laboratory and clinical data.
Girijala et al. (Thu,) conducted a review in Stroke. Female sex is associated with a higher incidence of stroke and more negative clinical outcomes compared to men, highlighting the need to understand differential physiology and epidemiology.