Preoperative posterior wall thickness was an independent risk factor for long-term survival after AVR, with 5-year rates of 81%, 94%, and 85% for PWTh ≤13, 14-17, and ≥18 mm, respectively (p=0.03).
Cohort (n=250)
Do preoperative M-mode echocardiographic findings predict mortality after aortic valve replacement in patients with aortic stenosis?
Preoperative M-mode echocardiographic parameters, particularly subnormal left ventricular end-diastolic diameter index and posterior wall thickness, are independent predictors of early and late mortality following aortic valve replacement for aortic stenosis.
p-value: p=0.03
To relate preoperative findings at M-mode echocardiography to preoperative clinical and haemodynamic status and to identify possible echocardiographic risk factors for mortality after aortic valve replacement (AVR), 250 patients with AVR for aortic stenosis (AS) were studied. In follow-up averaging 3.2 years there were 22 early ( or = 18 mm, respectively (p = 0.03). Prevalence of concomitant coronary artery disease (CAD) rose with decreasing PWTh. Angina pectoris in non-CAD patients was related to very high PWTh. Subnormal EDDI was associated with poor surgical outcome, and dilated, poorly contracting LV with congestive heart failure prior to AVR. The degree of LV hypertrophy seemed to be the dominant risk factor, but confounders included myocardial ischaemia due to CAD in low-grade hypertrophy or to hypertrophy per se. A hypothetically confounding factor is the reversibility potential of moderate or severe LV hypertrophy following AVR.
Lund et al. (Wed,) conducted a cohort in Aortic stenosis (n=250). Preoperative M-mode echocardiography was evaluated on Early (< 30 days) and late mortality (p=0.03). Preoperative posterior wall thickness was an independent risk factor for long-term survival after AVR, with 5-year rates of 81%, 94%, and 85% for PWTh ≤13, 14-17, and ≥18 mm, respectively (p=0.03).