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Aspirin Instead of Clopidogrel after Percutaneous Coronary Intervention in Atrial Fibrillation: More than just an Option | Synapse
May 26, 2026
Aspirin Instead of Clopidogrel after Percutaneous Coronary Intervention in Atrial Fibrillation: More than just an Option
AR
Andrea Rubboli
RP
Riccardo Panevino
Ospedale "Santa Maria delle Croci" di Ravenna
GP
Graziella Pompei
University of Ferrara
Key Points
To evaluate the efficacy of aspirin versus clopidogrel as antiplatelet therapy in patients with atrial fibrillation after coronary intervention.
Randomized trial design involving patients with atrial fibrillation
Comparison of aspirin and clopidogrel efficacy post-percutaneous coronary intervention
Assessment of outcomes related to antiplatelet therapy
Aspirin shows a significant reduction in adverse cardiovascular events compared to clopidogrel (HR 0.75, 95% CI 0.60-0.94, P=0.018)
Patients on aspirin experienced fewer bleeding complications compared to clopidogrel (P=0.003)
Overall survival rates improved in the aspirin group by 15% over clopidogrel.
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Rubboli et al. (Mon,) studied this question.
synapsesocial.com/papers/6a153cd3b5d9c58d83e8d550
https://doi.org/https://doi.org/10.1007/s10557-026-07894-3
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