Among 366 patients, baseline plasma ET-1 levels were associated with the need for revascularization in diabetic patients, and PCI was associated with a lower risk of cerebro/cardiovascular events.
Cohort (n=366)
Does revascularization by PCI reduce cerebro/cardiovascular events in patients with diabetes?
In patients with diabetes, revascularization by PCI is associated with a lower risk of short-term cerebro/cardiovascular events, and plasma ET-1 levels correlate with the need for revascularization.
Short-term follow-up for 366 patients (median of 4 months) showed that 132 developed one cerebro/cardiovascular event, predominantly among DM patients. Baseline ET-1 was not associated with higher risk of the first event. Notably, revascularization by PCI was associated with lower event risk in DM patients. Our study indicates that plasma ET-1 levels are associated with the need for revascularization in DM patients, with those undergoing PCI having a lower risk of initial cerebro/cardiovascular events.
Mayyas et al. (Sun,) conducted a cohort in Cardiovascular disease and diabetes mellitus (n=366). Plasma endothelin-1 (ET-1) levels and PCI was evaluated on Cerebro/cardiovascular event. Among 366 patients, baseline plasma ET-1 levels were associated with the need for revascularization in diabetic patients, and PCI was associated with a lower risk of cerebro/cardiovascular events.