The delta H-A interval was significantly longer during junctional tachycardia (9 ms) compared to AVNRT (-10 ms, P<0.00001), with a value ≥0 ms yielding 89% sensitivity and 83% specificity for JT.
Observational (n=35)
Does the delta H-A interval accurately differentiate atrioventricular nodal reentrant tachycardia from junctional tachycardia in patients undergoing electrophysiology study?
The delta H-A interval is a novel, reproducible electrophysiological measurement that can accurately differentiate junctional tachycardia from AVNRT.
Absolute Event Rate: 9% vs -10%
p-value: p=<0.00001
INTRODUCTION: Junctional tachycardia (JT) and atrioventricular nodal reentrant tachycardia (AVNRT) can be difficult to differentiate. Yet, the two arrhythmias require distinct diagnostic and therapeutic approaches. We explored the utility of the delta H-A interval as a novel technique to differentiate these two tachycardias. METHODS: We included 35 patients undergoing electrophysiology study who had typical AVNRT, 31 of whom also had JT during slow pathway ablation, and four of whom had spontaneous JT during isoproterenol administration. We measured the H-A interval during tachycardia (H-A(T)) and during ventricular pacing (H-A(P)) from the basal right ventricle. Interobserver and intraobserver reliability of measurements was assessed. Ventricular pacing was performed at approximately the same rate as tachycardia. The delta H-A interval was calculated as the H-A(P) minus the H-A(T). RESULTS: There was excellent interobserver and intraobserver agreement for measurement of the H-A interval. The average delta H-A interval was -10 ms during AVNRT and 9 ms during JT (P or= 0 ms had the sensitivity of 89%, specificity of 83%, positive predictive value of 84%, and negative predictive value of 88%. The delta H-A interval was longer in men than in women with JT, but no gender-based differences were seen with AVNRT. There was no difference in the H-A interval based on age <or= 60 years. CONCLUSION: The delta H-A interval is a novel and reproducibly measurable interval that aids the differentiation of JT and AVNRT during electrophysiology studies.
Srivathsan et al. (Thu,) conducted a observational in Atrioventricular Nodal Reentrant Tachycardia (AVNRT) and Junctional Tachycardia (JT) (n=35). Delta H-A interval measurement vs. AVNRT vs JT episodes was evaluated on Average delta H-A interval (p=<0.00001). The delta H-A interval was significantly longer during junctional tachycardia (9 ms) compared to AVNRT (-10 ms, P<0.00001), with a value ≥0 ms yielding 89% sensitivity and 83% specificity for JT.