Enantioselective Organocatalyzed α Sulfenylation of Aldehydes

The facile elaboration of optically active α-sulfanyl-substituted aldehydes makes their direct preparation from unmodified aldehydes and 1-benzylsulfanyl-1, 2, 4-triazole particularly valuable. The substituted aldehydes are formed with excellent enantioselectivities in the presence of sterically demanding chiral pyrrolidine derivatives as organocatalysts (see scheme). R, R′=H, alkyl, allyl, benzyl, Ph. Supporting information for this article is available on the WWW under http: //www. wiley-vch. de/contents/jc₂002/2005/z462101ₛ. pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.