Drug nonadherence is highly prevalent in hypertension and may undermine the benefits of antihypertensive agents, negatively impacting cardiovascular, cerebrovascular, and renal outcomes.
Does adherence to antihypertensive drugs improve blood pressure control and cardiovascular outcomes in patients with hypertension?
This review highlights the critical role of drug adherence in hypertension management and its significant impact on clinical outcomes.
: Adherence to treatment is now well recognized as a crucial key in the effectiveness of antihypertensive drugs; however, it is often overlooked in the management of hypertension because methodology to assess it is partly unreliable and limits its use in clinical practice. The available evidence suggests that nonadherence is highly prevalent in a chronic asymptomatic condition such as hypertension. It may undermine benefits expected from antihypertensive agents and therefore, may negatively impact cardiovascular, cerebrovascular and renal outcomes. In this review, we discuss the methodological issues related to the measurement of drug adherence in a research setting and clinical practice, the prevalence and the impact of drug nonadherence on blood pressure control and thus in apparent resistant hypertension, and on cardiovascular, cerebrovascular and renal outcomes.
Hamdidouche et al. (Fri,) conducted a review in Hypertension. Drug adherence was evaluated. Drug nonadherence is highly prevalent in hypertension and may undermine the benefits of antihypertensive agents, negatively impacting cardiovascular, cerebrovascular, and renal outcomes.
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