Secondary nephrogenic hypertension was associated with worse physical and mental health and higher rates of severe depression and anxiety compared to essential hypertension and healthy controls.
Observational (n=128)
Do patients with secondary (nephrogenic) hypertension have worse psychological state and quality of life compared to those with essential hypertension and healthy controls?
Patients with secondary (nephrogenic) hypertension experience worse psychological status, including more severe depression and anxiety, compared to those with essential hypertension and healthy controls.
p-value: p=<0.05
Objective: To evaluate the psychological state and quality of life of patients with different types of hypertension (essential and secondary, namely nephrogenic). Design and method: 98 patients with arterial hypertension (50 with essential and 48 with secondary due to chronic glomerulonephritis) were examined. The control group included 30 practically healthy individuals of appropriate age and sex. Psychological state was examined using the Beck Depression Inventory (BDI) and the State-Trait Anxiety Inventory (STAI). Quality of life was assessed using Medical Outcomes Study 36-Item Short-Form Health Survey (the SF-36 questionnaire). Results: According to Beck Depression Inventory patients with nephrogenic hypertension significantly more often had moderate and severe depression not only compared to the control group, but also patients with essential hypertension (p0.05). Severe trait anxiety (T-anxiety) was significantly more common in patients with secondary hypertension compared to both the control group and patients with essential hypertension (p0.05). The level of mental health was 5.6% and 12.1% lower than in the control group (p<0,05), respectively, with a tendency to significance depending on arterial hypertension etiology (0.05<p<0.1). Conclusions: Patients with arterial hypertension, regardless of its etiology, have worse quality of life and psychological status indicators. Patients with secondary hypertension were characterized by worse quality of life, a higher frequency of both severe depression and severe S- and T-anxiety.
Romanova et al. (Fri,) conducted a observational in Arterial hypertension (n=128). Secondary (nephrogenic) arterial hypertension vs. Essential hypertension and healthy controls was evaluated on Psychological state (depression and anxiety) and quality of life (physical and mental health) (p=<0.05). Secondary nephrogenic hypertension was associated with worse physical and mental health and higher rates of severe depression and anxiety compared to essential hypertension and healthy controls.