Decarboxylative fluorination of carboxylic acid derivatives has emerged as a powerful strategy for the synthesis of organofluorine compounds, particularly aryl fluorides and alkyl fluorides, which are widely utilized in pharmaceuticals, agrochemicals, and functional materials. These transformations can be achieved through a variety of approaches, including photoredox-catalyzed, transition-metalmediated, and thermally induced processes. This short review summarizes recent advances in decarboxylative fluorination reactions, highlighting representative synthetic methods, characteristic substrate scope, and mechanistic features underlying these transformations.
Uei et al. (Mon,) studied this question.